Search results for "Epidemiology of HCV infection"

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HCV infection and oral lichen planus: a weak association when HCV is endemic.

2004

Oral lichen planus (OLP), an immune-mediated disorder, has been reported as an extra-hepatic manifestation of Hepatitis C virus (HCV) infection, especially in HCV hyperendemic areas such as southern Europe and Japan. The aim of this study was to investigate from an epidemiological standpoint whether HCV infection is an important factor affecting the relative risk of OLP in a Mediterranean population or whether this relates to the degree of HCV endemicity. Two cohorts of OLP patients resident in two different regions of southern Italy (Campania and Sicily; n = 859) were evaluated for HCV infection status and categorized into five age classes to respective region-matched controls. No signific…

AdultMalemedicine.medical_specialtyEpidemiology of HCV infectionEndemic DiseasesHepatitis C virusPopulationHepacivirusBiologymedicine.disease_causestomatognathic systemVirologyEpidemiologyPrevalencemedicineHumanseducationeducation.field_of_studyHepatologySignificant differencevirus diseasesHepatitis C AntibodiesMiddle Agedmedicine.diseaseHepatitis Cdigestive system diseasesstomatognathic diseasesInfectious DiseasesItalyRelative riskImmunologyOral lichen planusEtiologyWeak associationFemaleOral lichen planusHepatitis C viruLichen Planus Oral
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Epidemiological profile of 806 Italian children with hepatitis C virus infection over a 15-year period

2007

BACKGROUND & AIMS: The natural course of chronic hepatitis C (CHC) in children is not well understood. The aim of this study was to assess the long-term course of CHC in a large sample of otherwise healthy children. METHODS: From 1990 to 2005, 504 consecutive antihepatitis C virus (HCV)-positive children were enrolled at 12 centers of a national observatory and were followed up retrospectively/prospectively. RESULTS: Putative exposure was perinatal in 283 (56.2%) cases, parenteral in 158 (31.3%), and unknown in 63 (12.5%). At baseline, 477 (94.6%) cases were HCV RNA seropositive, 118 (24.7%) of which were treated with standard interferon alpha. Ten years after putative exposure, the out…

MalePediatricsEpidemiologyInfectious Disease TransmissionCHILDRENHepacivirusmedicine.disease_causeGENOTYPES HCVRisk FactorsEpidemiologyPrevalenceVerticalChronicYoung adultChildHCV infection in childrenbiologyHepatitis C virus (HCV)Hepatitis CANTI-HCVHepatitis CItalyChild PreschoolHCVFemaleViral diseaseAdultmedicine.medical_specialtyEpidemiology of HCV infectionGenotypepediatricsHepatitis C virusSocio-culturaleEnzyme-Linked Immunosorbent AssayFlaviviridaeHCV vertical transmissionmedicineHumansBlood TransfusionSex DistributionPreschoolRetrospective StudiesEpidemiology of HCV infection; HCV infection in children; HCV vertical transmission; Hepatitis C virus (HCV); Adult; Blood Transfusion; Child; Child Preschool; Enzyme-Linked Immunosorbent Assay; Female; Genotype; Hepacivirus; Hepatitis C; Hepatitis C Antibodies; Hepatitis C Chronic; Humans; Infant; Infectious Disease Transmission Vertical; Italy; Male; Prevalence; Retrospective Studies; Risk Factors; Sex Distribution; HepatologyHepatologybusiness.industryHIVInfantRetrospective cohort studyHepatitis C AntibodiesHepatitis C Chronicmedicine.diseasebiology.organism_classificationHEPATITIS HCVInfectious Disease Transmission VerticalEl NiñoImmunologybusiness
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